The severed chains
نویسندگان
چکیده
منابع مشابه
Calpain activity promotes the sealing of severed giant axons.
A barrier (seal) must form at the cut ends of a severed axon if a neuron is to survive and eventually regenerate. Following severance of crayfish medial giant axons in physiological saline, vesicles accumulate at the cut end and form a barrier (seal) to ion and dye diffusion. In contrast, squid giant axons do not seal, even though injury-induced vesicles form after axonal transection and accumu...
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NEUMANN in 1868 proposed the idea that severed peripheral nerve degenerates centrifugally; i.e., the degenerative processes start at the cut end and progress slowly towards the periphery. This view, opposing the conception of simultaneous degeneration advanced by Lent in 1856, started a controversy as yet unsettled. Most of the arguments on both sides have been based on histological evidence-on...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2004
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2004.07.028